Otogenes – diagnostic, predictive or carrier

Precision, personalised DNA diagnostics and treatment reports for hearing and balance professionals

Genomic hearing and balance healthcare reports. Test, don’t guess.

Genetic technology and large neuroscience datasets to help with inner ear disorders.

Our genomic driven AI reports for hearing and balance medical professionals access cutting-edge research and to confirm traditional and enable pipeline treatments without compromising integrity, privacy and personalised healthcare.

Otology is undergoing a quiet revolution. Your doctor can access the vast scientific literature, but has limited time to apply it directly to you. However, AI and clinical grade DNA technology opens the way for personalised, precision medicine.

Otogenex reports are a key medical tool, matching large datasets to a patient’s own DNA in doctor-to-doctor reports, a little like having an otogenius in the clinic.

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Our History…

Our work Contact Us

Otogenex started with a quest to find the cause of Meniere’s disease, a devastating inner ear disorder. Its founder, Stephen Spring was diagnosed with the condition in midlife. By mining scientific literature from experts around the world, over time, he came to understand molecular and immunological processes that cause endolymphatic hydrops are genetically determined.

The condition is impossible to understand without work of Dr Irv Arenberg, Emeritus Prof. William “Bill” Gibson and audiologists Celene McNeill who published papers dispelling myths about the disorder. More recently, Prof. Antonio Lopez Escamez, a pioneer in inner ear genetics has published nearly a 100 papers in peer reviewed journals.

Clinical use of genetic reporting is common in some specialities, but not widespread in otolaryngology. In the spirit of all pioneering pursuits, a portion of our income is targeted to research and education to help improve the millions lives affected by hearing and balance disorders.

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LATEST TECHNOLOGY

DNA Sampling

Otogenex takes a liquid biopsy approach, where a saliva sample is collected by the audiologist or clinician and sent to an accredited laboratory for sequencing a patient’s DNA. The sample consists of millions of base pairs of DNA, which is then processed with machine bioinformatics and compared to vast datasets using mathematical analysis to identify disease related gene sequences. We then produce a personalised, precision medicine report to assist with diagnoses and individualised treatment.

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PATIENTS

Conditions

Genomic reports can assist with diagnoses, treatment and prevention of a wide range of otology related conditions such as Meniere’s disease, syndromic and none syndromic hearing loss, hearing loss and otoxic risk identification, migraine and its hearing and balance variants, tinnitus and age related hearing loss.

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CASES STUDIES

Hearing and balance is in our DNA

DNA diagnostics impacts real-world otolaryngologic challenges. Each report augments traditional methods to complete the clinical picture and sheds new light using the transformative power of precision medicine.

OtoGenie Leveraging DNA Data for Better Patient Hearing Outcomes

Potential Use Reports: Beyond Surface Sounds – A Teacher’s Rediscovery of the Auditory World

Scenario: A Teacher’s Unexpected Silence – Envision Tom, a passionate 65-year-old retired teacher, who has spent decades immersed in the cacophony of lively classrooms. Post-retirement, he dreams of peaceful days filled with the sounds of nature and the laughter of grandchildren. However, an unforeseen challenge arises: a sudden and profound [...]

Potential Use Case: The Genetic Echo – A Family’s Quest for Auditory Clarity

Scenario: A Family Legacy of Muffled Sounds – Picture a family, the Smiths, with a lineage woven with tales of hearing challenges, spanning three generations. From grandparents to grandchildren, the narrative remains consistent: unexplained hearing anomalies that puzzle and concern. The younger generation, eager to shield themselves from a similar [...]

Potential Use Case: Deciphering the Genetic Melody – A Pianist’s Path to Clearer Hearing

Scenario: A Young Pianist’s Challenge – Imagine a 28-year-old accomplished pianist, enveloped in the world of music. But, a looming challenge emerges: over a short span, she experiences unexplained, progressive hearing loss. The melodies she once effortlessly played begin to blur into a concerning silence. [...]